Blog | Creyos | Cognitive Testing for Better Brain Health

How Creyos Meets the Alzheimer’s Association Recommendations for Cognitive Care

Written by Avi Meehan | Mar 19, 2026 6:48:27 PM

As dementia rates continue to rise worldwide, healthcare organizations are seeking ways to streamline the clinical implementation of dementia assessments. To help meet this demand, the Alzheimer's Association has developed recommendations for cognitive assessment that recognize the role of computerized screens in diagnostic testing.

In this post, we will look at the ways in which Creyos upholds these recommendations and supports rapid, scientifically backed cognitive screening for dementia in primary care.

Key Takeaways:

  • The Alzheimer’s Association recommends the use of cognitive testing tools that are scientifically validated, equal to or better psychometric ability than the MMSE, can be administered in under five minutes, and are easy to administer by non-physician staff without risk of educational, language, and/or cultural bias
  • The Creyos Dementia Assessment is aligned with these clinical practice guidelines for dementia screening in primary care
  • Further guidelines for digital dementia screening will be coming soon from the Alzheimer’s Association

What are the Alzheimer’s Association Recommendations for Dementia Screening?

The Alzheimer’s Association recommendations for dementia screening focus on administration time and ease, as well as scientific validation. These clinical practice guidelines apply to both pen-and-paper and digital cognitive tests, which screen for dementia, mild cognitive impairment (MCI), and other conditions related to cognitive decline.

To meet the standards of the Alzheimer’s Association, clinical assessments should have:

  • An administration time of less than or equal to 5 minutes
  • Validation in a primary care or community setting
  • Psychometric equivalence or superiority to the Mini-Mental State Exam (MMSE)
  • Easy administration by non-physician staff and be relatively free of educational, language, and/or cultural bias.

Creyos Health: Trusted Screening for Alzheimer’s Disease and Mild Cognitive Impairment

The Creyos Dementia Assessment and Care Plan is designed to support early diagnosis and ongoing monitoring of Alzheimer’s disease, dementia, and mild cognitive impairment (MCI). Built for seamless clinical implementation, our suite of scientifically validated cognitive tools rapidly gathers objective data without adding to your administrative burden.

Short Administration Time

The initial two-task Creyos screener can be used to detect subtle cognitive impairment in under 5 minutes. If results suggest that further testing may be warranted, providers can also administer a more comprehensive 20-minute cognitive assessment to help better understand if a patient may meet the diagnostic criteria for mild or major neurocognitive disorders.

Individual online cognitive tasks can also be performed for quick, domain-specific insight related to areas that patients may have previously had difficulty with. This flexible approach allows providers to easily re-administer assessments for longitudinal tracking and monitoring of cognitive health.

In practice, Creyos helped Yukon Neurology reduce full cognitive assessment time from six hours to two. These efficiencies enabled clinicians to see an average of 30 patients per day and complete 10 neuropsychological exams weekly without compromising quality of care.

Scientific Validation

Our cognitive tasks are based on more than 30 years of research and have been used in over 400 peer-reviewed studies. Currently, over ten thousand healthcare providers and researchers use Creyos to support the diagnosis of dementia and other neurological conditions or diseases.

In fact, we provided the screening tools for the world’s largest dementia trial—the Maintain Your Brain study run by the Center for Healthy Brain Aging (CHeBA). Over the course of three years, thousands of people remotely participated in online cognitive assessments, gathering objective data on the cognitive impact of lifestyle choices to better understand risk factors for dementia.

Alignment with the MMSE

Creyos can be used either as a replacement or support tool for the Mini-Mental State Exam (MMSE). While both tests are valuable for their brevity and easy administration, the Creyos Dementia Assessment has been shown to be more sensitive than the MMSE for detecting dementia and MCI.

Ease of Administration

The Creyos cognitive tasks do not require training to administer and can be performed by non-physician staff in primary care settings. Because our gamified tasks are all digital, patients can complete them either in-clinic or from the comfort of their homes.

Results are automatically integrated into patients’ EHRs in the form of easy-to-read reports. Compared to traditional pen-and-paper testing.

Types of Screening Tools for Diagnostic Testing

The Alzheimer’s Association’s clinical practice guidelines include four types of tools for diagnostic testing:

  • Patient assessment tools: Gather subjective insights into how people living with dementia are experiencing their symptoms. Understanding a patient’s unique needs and wants is essential for delivering patient-centered care.
  • Informant assessment tools: Gather insight from family members, close friends, and other personal caregivers. More than 75% of caregivers for dementia patients play a part in navigating their healthcare.
  • Computerized cognitive tests: Assess objective cognitive function insights from data that cannot be captured by traditional pen-and-paper tests. Deeper guidelines from the Alzheimer’s Association regarding these clinical assessments will be coming soon.
  • Depression screens and mood assessments: Many people living with dementia experience mood-related symptoms. Mental and behavioral health questionnaires can help identify if mood changes are connected to cognitive decline.

All of these screening tools play a part in diagnostic testing but are unable to provide a formal diagnosis of mild cognitive impairment or dementia alone. If a patient fails any of these screens, further evaluation or a specialist referral for in-depth neurocognitive testing may be warranted.

The Creyos Dementia Screener & Assessment Protocol

The Creyos dementia protocol combines cognitive, functional, and behavioral testing to provide information about symptoms of mild cognitive impairment and dementia.

Here’s how Creyos meets the Alzheimer’s Association's recommendations:

Online Cognitive Tasks and Assessed Domains

Our brief, gamified online cognitive tasks assess several different aspects and domains of cognitive ability. Each task is quick to complete and can be administered either in clinic or remotely, with instant scoring and comparisons to large-scale normative data.

If cognitive impairment is detected by the initial two-task screener, clinicians can continue on to administer the complete dementia assessment. The Creyos Dementia Assessment measures:

  • Episodic memory
  • Visuospatial working memory
  • Attention and concentration
  • Verbal short-term memory
  • Mental rotation
  • Response inhibition

Analyzing performance across multiple domains helps distinguish normal aging from mild cognitive impairment or dementia.

The Creyos cognitive tasks are sensitive enough to flag early signs of cognitive decline, including symptoms associated with mild cognitive impairment. With early detection, providers can address modifiable risk factors and initiate care planning sooner—which means better support for patients and their families.

Behavioral and Mental Health Questionnaires

The Creyos Dementia Assessment also includes validated questionnaires that help flag mental health concerns related to DSM-5 diagnostic criteria for neurocognitive disorders and other risk factors that may influence cognition or complicate diagnosis.

Included questionnaires assess:

  • Informant-reported subjective cognitive change (IQCODE-SR)
  • Functional independence and instrumental activities of daily living (IADL questionnaire)
  • Depression symptoms (PHQ-9)
  • Anxiety symptoms (GAD-7)

The clinical implementation of these questionnaires helps providers identify comorbid symptoms that may be related to neurocognitive disorders, allowing for higher-quality care.

Care Planning and Longitudinal Monitoring

After cognitive tasks and behavioral assessments are completed, results are transformed into easy-to-read reports that automatically upload into patients’ EHRs. Along with the Creyos Dementia Screener and Assessment Protocol, clinical judgments and interviews should be used in conjunction to reach diagnostic conclusions regarding a patient’s condition.

Based on those results, providers can use Creyos’ templates to quickly generate detailed, personalized cognitive care plans that align with Medicare. These include lifestyle advice to address risk factors, medication management, and caregiver education.

Individual cognitive tasks can be re-administered over time to gather essential longitudinal data and identify meaningful changes in performance, monitor for mild or significant decline, and evaluate a patient’s responsiveness to treatment.

Implementing Cognitive Testing into Primary Care

As dementia rates continue to rise, it is essential for cognitive screens to become a part of routine primary care. With the help of digital testing tools, providers can confidently identify cognitive impairment and early signs of decline while alleviating administrative burden.

Creyos delivers fast cognitive assessment with simple clinical implementation that aligns with the Alzheimer’s Association recommendations. Contact us today to learn how we can help deliver clinical assessments while streamlining workflows. 

 

 

Reviewed by Mike Battista, Director of Science & Research at Creyos

Mike Battista specializes in brain health, cognition, and neuropsychological testing. He received his PhD in personality and measurement psychology at Western University in 2010 and has been doing fun and useful stuff in the intersection between science and technology ever since.